Mouth Sores—Child Care and Schools

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What are the causes of mouth sores?

Herpes simplex, hand-foot-and-mouth disease, and thrush cause mouth sores. Mouth sores can also have noninfectious causes (eg, canker sores, autoimmune disorders).

What is herpes simplex?

  • Herpes simplex is a virus that can cause a variety of symptoms in different age-groups.

  • In early childhood, herpes simplex most commonly causes blister-like sores in the mouth; around the lips; and on skin that is in contact with the mouth, such as a sucked thumb or finger.

  • Virus may be shed by children and adults with no signs or symptoms.

  • Herpesviruses stay in the body without symptoms after initial infection; recurrent disease may occur because of a variety of triggers, such as stress, cold, or sunlight.

  • See Herpes Simplex (Cold Sores) Quick Reference Sheet for more details.

What is hand-foot-and-mouth disease?

  • A virus (enterovirus) that can cause a rash on the hands and feet and shallow ulcers on the inside of the mouth.

  • See Hand-Foot-and-Mouth Disease Quick Reference Sheet for more details.

What is thrush?

  • White patches on the inside of the cheeks, gums, and tongue caused by a fungus/yeast called Candida .

  • See Thrush (Candidiasis) Quick Reference Sheet for more details.

What are canker sores?

  • Shallow ulcers in the mouth and inside of lips and gums.

  • The cause is not known but may be due to immune system factors, family history, or related to trauma from biting the inside of the cheek or lip.

  • These sores are not contagious.

What are the signs or symptoms?

  • Herpes is the most severe of these conditions, and a primary or initial infection may result in

    • – Fever

    • – Irritability

    • – Tender, swollen lymph nodes

    • – Painful, small, fluid-filled blisters (vesicles) in the mouth and on the gums and lips

    • – Pain with eating and swallowing

    • – Vesicles that weep clear fluid, bleed, and are slow to crust over

  • Canker sores and hand-foot-and-mouth disease may cause pain with eating and swallowing.

  • Some children will drool excessively because it hurts to swallow the saliva.

  • Thrush does not usually cause discomfort unless the infection is severe.

What are the incubation and contagious periods?

See individual Quick Reference Sheets for herpes simplex, hand-foot-and-mouth disease, and thrush. Canker sores are not known to be contagious.

How are they spread?

See individual Quick Reference Sheets for herpes simplex, hand-foot-and-mouth disease, and thrush.

How do you control them?

See individual Quick Reference Sheets for herpes simplex, hand-foot-and-mouth disease, and thrush. There is no cure for canker sores. They must run their course for 1 or 2 weeks. Pain medication, such as acetaminophen (eg, Tylenol) or ibuprofen (eg, Advil, Motrin), may be used. Alcohol-free mouthwashes or oral gels can be used to help with symptoms and healing. Oral lidocaine can be absorbed through the mouth and may cause systemic toxicity; therefore, it should not be used, particularly for children younger than 3 years.

What are the roles of the educator and the family?

  • Report these conditions to the staff member designated by the early childhood education program or school for decision-making and action related to care of ill children and staff members. That person, in turn, alerts possibly exposed family and staff members to watch for symptoms.

  • Stress the importance of good hand hygiene and other measures aimed at controlling the transmission of infected secretions (eg, saliva, tissue fluid, fluid from a skin sore).

  • Wash and sanitize mouthed toys, bottle nipples, and utensils that have come into contact with saliva or have been touched by children who are drooling and put fingers in their mouths.

  • Try to avoid touching cold sores with hands, which is difficult but should be attempted. When sores have been touched, careful hand hygiene should follow immediately, using good hand-hygiene technique listed in Chapter 2 of Managing Infectious Diseases in Child Care and Schools: A Quick Reference Guide, 7th Edition .

Exclude from educational setting?

No, unless

  • For herpes simplex and hand-foot-mouth disease, when the child has mouth ulcers and blisters and does not have control of drooling. If a health practitioner determines the sores are not infectious (eg, canker sores), the child should not be excluded from class, even with drooling.

  • The child is unable to participate and staff members determine they cannot care for the child without compromising their ability to care for the health and safety of the other children in the group.

  • The child meets other exclusion criteria (see Conditions Requiring Temporary Exclusion in Chapter 4 of Managing Infectious Diseases in Child Care and Schools: A Quick Reference Guide, 7th Edition ).

Note: Children and educators with recurrent infection (ie, herpes simplex cold sores) do not need to be excluded as long as there is no drooling.

Readmit to educational setting?

Yes, when all the following criteria are met:

  • When a child with infectious ulcers or vesicles inside the mouth is no longer drooling or, if still drooling, the ulcers or vesicles have resolved. A child with vesicles (blisters) on the body can return once these areas are covered with clothing or a bandage.

  • When exclusion criteria are resolved, the child is able to participate, and staff members determine they can care for the child without compromising their ability to care for the health and safety of the other children in the group.

Disclaimer

Adapted from Managing Infectious Diseases in Child Care and Schools: A Quick Reference Guide , 7th Edition.

The American Academy of Pediatrics (AAP) is an organization of 67,000 primary care pediatricians, pediatric medical subspecialists, and pediatric surgical specialists dedicated to the health, safety, and well-being of all infants, children, adolescents, and young adults.

Any websites, brand names, products, or manufacturers are mentioned for informational and identification purposes only and do not imply an endorsement by the American Academy of Pediatrics (AAP). The AAP is not responsible for the content of external resources. Information was current at the time of publication. The information contained in this publication should not be used as a substitute for the medical care and advice of your pediatrician. There may be variations in treatment that your pediatrician may recommend based on individual facts and circumstances.

AAP Feed run on: 3/31/2026 Article information last modified on: 3/31/2026